Intergenerational effect of shortterm spaceflight inside rats

The detoxifying mixture can also be used on animals grazing in territories adjacent to Proton-M launch sites for preventive and therapeutic purposes.
The antitox+Vitamin E-selenium detoxifying mixture significantly decreases the residual 1,1-DMH level in organs and tissues of animals and increases the nutritional value of rabbit meat in subacute poisoning. The detoxifying mixture can also be used on animals grazing in territories adjacent to Proton-M launch sites for preventive and therapeutic purposes.
Intoxication of arsenic in rats is known to result in neurological effects as well as liver and kidney dysfunction.
has been identified for its medicinal properties. The aim of the study was to investigate the protective effect of aqueous seed extract of
on sodium arsenite-induced memory impairment, liver, and kidney functions in rats.
The experiment was divided into short-term treatment (45 days) and long-term treatment (90 days), with each group divided into nine sub-groups consisting of six animals each. Sub-groups 1 and 2 served as normal, and N-acetylcysteine (NAC) controls, respectively. Sub-groups 3-9 received sodium arsenite in drinking water (50 mg/L). In addition, sub-group 4 received NAC (210 mg/kg b.wt) orally once daily, sub-groups 5-7 received aqueous seed extract of
(350 mg/kg b.wt, 530 mg/kg b.wt, and 700 mg/kg b.wt) orally once daily and sub-groups 8 and 9 received a combination of NAC and aqueous seed extract of
350 mg/kg b.wt and 530 mg/kg b.wt) orally once daily. Following tumber of surviving neurons in the CA1 and CA3 regions also increased on treatment with
. Serum ALT, serum urea, and serum creatinine levels showed significant improvement on long-term treatment with
.
The seed extract of M. pruriens showed significant enhancement in memory and learning. The number of surviving neurons in the CA1 and CA3 regions also increased on treatment with M. pruriens. Serum ALT, serum urea, and serum creatinine levels showed significant improvement on long-term treatment with M. pruriens.
This study was conducted to determine the anthelmintic activity of aqueous and ethanol extracts of
bark against
.
Ethanol extract of bark (E.E.B.) waste and aqueous extract of bark (A.E.B.) waste of
(at concentrations 0, 0.2, 0.4, 0.8, 1, 2.5, and 5%) and albendazole (2 mg/ml) as the positive control were placed in separate Petri dishes (50 mm). Twenty
worms were placed in Petri dishes and incubated at 37°C for 0.5, 1, 2, 3, 4, 5, 6, and 12 h. Mortality of each worm was ensured by pressing the body of the worm with a pair of tweezers and keeping it in lukewarm water for 5 min before declaring it dead. Mortality is defined as amount of death individuals and time of mortality of each worm was recorded. The parasites were then observed using scanning electron microscopy (SEM) at an accelerating voltage of 15 Kv. Statistical analysis was performed using SPSS 21.0 software, two-way ANOVA followed by Tukey's test to detect significant differences (p<0.05). The result was expressed as the mean ± standard deviation.
The E.E.B. and A.E.B. of
contained active compounds, such as tannin, alkaloid, flavonoid, saponin, steroid, and triterpenoid. E.E.B. had a higher content of phenol, while A.E.B. had a higher content of flavonoid. In this study,
showed a significant effect (p=0.00) on
. E.E.B. (0.8%) was able to exterminate
completely after 6 h, more effective than A.E.B. (5%) while the positive control requires (2 mg/ml) after 2 h. SEM analysis of the worm treated with E.E.B. MSC-4381 clinical trial and A.E.B. showed damaged cuticle structure.
The aqueous and ethanol extracts of
bark waste demonstrated anthelmintic activity against
.
The aqueous and ethanol extracts of P. falcataria bark waste demonstrated anthelmintic activity against H. contortus.
Bullfighting is booming in South Thailand, attracting tourists, and stimulating local economies. The bulls are well raised and practiced, but in many cases, the owners lack knowledge and understanding of the prevention of animal diseases, including parasitic infections. This study aimed to determine the occurrence of gastrointestinal (GI) parasite infection in fighting bulls.
A total of 1501 fecal samples were collected from bulls aged 2-5 years visiting the animal hospital of Prince of Songkla University during 2016-2019. The formalin ethylether concentration method was used to detect GI parasites in feces.
The overall rate of GI parasite infection was 94.27%. Rumen fluke eggs were detected in 97.17% of all infected animals, followed in prevalence by strongyles (26.29%),
spp. (2.83%),
spp. (2.47%),
spp. (0.35%), and
spp. (0.14%). Two protozoan genera were identified,
(6.64%) and
spp. (3.53%). Coinfection was observed in 33.99%. The five most common coinfections were rumen fluke with snthelmintic drugs as well as rotation of anthelmintic drug that have different chemical agent to prevent further drug resistance should be considered. The promotion of bull health management is highly recommended to protect humans from zoonotic diseases.
Fracture cases significantly increase recently, demanding high quality of bone graft materials. This research aimed to evaluate the effects of bone types, particle sizes, and gamma irradiation doses on morphological performance and cell viability of feline demineralized freeze-dried bone allograft (DFDBA) through an
study.
Feline DFDBA derived from feline cortical and cancellous long bones was processed into four different sizes Group A (larger than 1000 µm), B (841-1000 µm), C (420-840 µm), and D (250-419 µm) for each type of bones. The materials were then irradiated with two doses of gamma rays, 15 and 25 kGy, resulting in 16 variants of feline DFDBA. The surfaces of each material were then observed with the scanning electron microscope (SEM). The
evaluation of feline DFDBA was then performed using 3-(4,5-dimethythiazol-2)-2,5-diphenyltetrazolium bromide (MTT) assay with calf pulmonary artery endothelial cells.
The MTT assay results showed that the lowest inhibition rate (14.67±9.17 %) achieved by feline DFDBA in Group A derived from cortical bones irradiated with 15 kGy. Group D generally showed high inhibition rate in both cancellous and cortical bones, irradiated with either 15 or 25 kGy. The SEM results showed that cancellous and cortical bones have numerous macropores and micropores structure in 170× and 3000×, respectively.
The material derived from cortical bones in Group A (larger than 1000 µm in particle size) irradiated with 15 kGy is the best candidate for further development due to its abundance of micropores structure and ability in preserving the living cells.
The material derived from cortical bones in Group A (larger than 1000 µm in particle size) irradiated with 15 kGy is the best candidate for further development due to its abundance of micropores structure and ability in preserving the living cells.